Asthma Market to Witness the Highest Growth Globally in Coming Years

Asthma is a respiratory condition, where the airways become inflamed and narrow, which can cause a serious and incurable condition if left untreated. Breathlessness, wheezing and coughing are some of the symptoms of asthma and it can be controlled by avoiding triggers and with the help of drug therapy. Environmental triggers may vary from consumer to consumer but it can include exercise, smoke, cold air and other allergens such as pollen, dust mites, and infections. The wheezing in asthma begins when the chemicals present in the lungs overreact to the dust mites, cold air and exercise.

According to Centers for Disease Control and Prevention (CDC), asthma is an ordinary chronic airway disorder which is characterized by swelling of air passages that convey air from mouth and nose to lungs. Asthma is caused generally due to allergies leading to inflammation of lungs. GlaxoSmithKline Pharmaceuticals Limited and Novartis AG are developing once-a-day combination products that are longer acting than currently available drugs and more suitable for patients due to its advantage of being taken only once a day.

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Based on drug class, the global asthma market can be categorized bronchodilators, combination therapies, mast cell stabilizers, leukotriene antagonists and immunosuppressants. On the basis of route of administration, the global market is segmented into oral, inhaled and other route of administrations.

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Daily exposure to hazardous working environment, influx of pollutants in the air, increase in population susceptible to indoor air pollutants, increase in disposable income, increasing population of smokers, improved healthcare facility, and growing aging population are some of other the major factors that are driving the growth of asthma market. Factors that are restraining the growth of asthma market are high cost of asthma treatment, patent expiry of many best-seller brands and long treatment continuation. Additionally, lack of diagnostic tools for reliable asthma diagnosis in young children is also limiting the growth of global asthma market.

Some of the major competitors of global asthma market are, Ono Pharmaceutical Co., Ltd., GlaxoSmithKline plc, Teva Pharmaceutical Industries Ltd. Merck & Co., Inc., Astrazeneca plc, Sunovion Pharmaceuticals, Inc., Novartis AG, Boehringer Ingelheim GmbH, Koninklijke Philips N.V., and F. Hoffmann La-Roche Ltd.

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Immunotherapy Drugs Market Analysis by Stages, Drug Class, Company Profile, Phase of Development, Clinical Trial, Preclinical Research & Discovery Stage Insights

The global immunotherapy drugs market valued $106.1 billion revenue in 2017 and is projected to register a CAGR of 13.6% during the period 2018–2023. Surge in the prevalence of chronic diseases, and thriving demand and development of monoclonal antibodies (mAbs) are the key factors driving the market growth.

Checkpoint inhibitors and vaccines are the two major types of immunotherapy drugs analyzed in the report. Of these, checkpoint inhibitors held a larger share in the immunotherapy drugs market, accounting for 66.3% in 2017. Checkpoint inhibitors are the first preference for the treatment of chronic diseases, as they provide better and effective treatment results. These drugs act directly on site of action, without delaying the effect of medicine, and are thus being highly adopted for the treatment of several diseases. Some of the major checkpoint inhibitors brand available in the market are Humira, Rituxan/MabThera, Herceptin, Remicade, and Enbrel.

Hospitals and clinics were the key end users in the immunotherapy drugs market, with 81.0% contribution in 2017. The adoption of immunotherapy drugs has been increasing in hospitals and clinics, owing to growing patient population, increasing healthcare expenditure, and rising prevalence of chronic diseases, leading to dominate the end-user segment.

North America was the largest immunotherapy drugs market during the historical period, with more than 50.0% contribution in 2017. This can be attributed to the increasing per capita healthcare spending, surging geriatric population, rising prevalence of chronic diseases, and growing presence of market players in the region. Furthermore, factors such as growing research collaborations, increasing number of research laboratories, and growing direct and indirect investments in research and development (R&D) by pharmaceutical and biotechnology companies will also support the growth of the regional market in the coming years.

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Globally, the rising prevalence of chronic diseases is a major healthcare burden that effects high income nations as well as low and middle-income countries (LMIC). The impact of these diseases can be ascertained from the fact that cancer is estimated to lead to 9.6 million deaths in 2018, as reported by the World Health Organisation (WHO). The organisation further stated that around 70% of deaths from cancer occur in LMIC.

Several drugs manufactured by market players for the treatment of chronic diseases are under clinical trials. Thus, increasing use of immunotherapy drugs to combat the rising prevalence of chronic diseases is an important factor driving the market demand. Moreover, thriving demand and development of mAbs, rise in the implementation of target therapy, and increasing availability of biosimilars are also contributing to the growth of the immunotherapy drugs market.

The report provides epidemiology analysis for cancer, autoimmune and inflammatory diseases, and infectious diseases. According to the International Agency for Research on Cancer (IARC) in 2018, 18.1 million people are estimated to be suffering from cancer globally, which is expected to reach 29.5 million by 2040. Another study conducted by the American Medical Association (AMA) between 2005–2015, reported that the incident of cancer cases increased by 33% during this period, of which 16.4% of the cases were due to aging population.

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The report also covers pricing and reimbursement scenario for immunotherapy drugs on the universal level and for major countries such as the U.S., Belgium, the U.K., France, Italy, Spain, Japan, China, and Australia. For instance, a reimbursement scenario in the U.K. has impacted the cost of the drugs. Keytruda is an immunotherapy drug used for the treatment of melanoma, non-small cell lung cancer (NSCLC), head and neck squamous cell cancer (HNSCC), urothelial carcinoma, gastric cancer, and cervical cancer. Keytruda generally costs up to $84,000 to the patients. To reduce the cost of this drug, the National Health Service (NHS) England; a publicly funded national healthcare system, and Merck & Co. Inc. entered into an agreement in June 2018, to reimburse the cost of this drug and provide it for routine use as per the National Institute for Health and Care Excellence (NICE) recommendations. NICE recommends NHS to provide reimbursements for this drug and make it affordable for the patients.

Some of the other leading players operating in the global immunotherapy drugs market are F. Hoffmann-La Roche Ltd., AbbVie Inc., AstraZeneca PLC, Merck & Co. Inc., GlaxoSmithKline plc, Novartis International AG, Johnson & Johnson, Amgen Inc., Bristol-Myers Squibb Company, Eli Lilly and Company, Sanofi, Medigene AG, C. H. Boehringer Sohn AG & Co. KG, Takeda Pharmaceutical Company Limited, and Celgene Corporation.

  

MARKET SEGMENTATION
By Therapy Area

·         Cancer

o    Solid Tumor

o    Malignant

·         Autoimmune & Inflammatory Diseases

·         Infectious Diseases

·         Others

By Type of Drug

·         Monoclonal Antibodies

·         Adult Vaccines

o    Preventive Vaccines

o    Therapeutic Vaccines

·         Checkpoint Inhibitors

·         Interferons Alpha & Beta

·         Interleukins

·         Others

By End User

·         Hospitals

·         Clinics

·         Others

Geographical Segmentation

·         North America

o    U.S.

o    Canada

·         Europe

o    Germany

o    U.K

o    France

o    Italy

o    Spain

o    Rest of Europe

·         Asia-Pacific

o    China

o    India

o    Japan

o    Rest of Asia-Pacific

·         Latin America

o    Brazil

o    Mexico

o    Rest of Latin America

·         Middle East & Africa (MEA)

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Needle-Free Diabetes Management Market Comprehensive Review of its Top Companies, Investment Trend, Growth Opportunities, Drivers, Technology and Future Prospects – Chemical Report

Needle-Free Diabetes Management Market Comprehensive Review of its Top Companies, Investment Trend, Growth Opportunities, Drivers, Technology and Future Prospects – Chemical Report

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