Rising Disease Prevalence to Drive Age-Related Macular Degeneration Market Forward

Registering a CAGR of 7.6% during the forecast period (2016–2022), the global age-related macular degeneration (AMD) market is projected to garner $8.9 billion by 2022, significantly growing from $5.3 billion in 2015. The market is experiencing growth due to the rising geriatric population, growing pipeline for AMD therapeutics, surging chronic disease prevalence, and increasing healthcare expenditure. Age-related macular degeneration is a retinal disorder, which is indicated by changes in the fundus of the eye. It commonly affects the elderly, in which, first, the central vision becomes blurred, which ultimately leads to blindness. 

Based on type, the age-related macular degeneration market is bifurcated into wet AMD and dry AMD. Between the two, during the historical period (2012–2015), the larger revenue in the market was generated by the wet AMD type. This type of AMD is caused due to the abnormal growth of blood vessels from the choroid layer, which is situated beneath the macula. It is also known as neovascular macular degeneration, and even though it accounts for only 10–15% of AMD cases, it is expected to be the faster growing category in the forecast period.

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With the rising awareness about the disease, more funding is being allocated in the research and development of AMD therapeutics. This is resulting in the increase in the number of AMD pipeline drugs. Currently, the U.S. Food and Drug Administration has not approved any drug in the age-related macular degeneration (AMD) market for dry age-related macular degeneration. Therefore, the need to investigate more compounds with possible therapeutics properties is rising. Some of the major investigational compounds in the market are Roche/Genentech’s lampalizumab, MacuCLEAR’s MC1101, and Allergan’s brimonide implant.

Therefore, the market for age-related macular degeneration is predicted to register remarkable growth in the forecast period with the rising prevalence of this disease and surging geriatric population.

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Increasing Prevalence of Benign Prostatic Hyperplasia in American Men Driving Demand for BPH Treatment Procedures

Benign Prostatic Hyperplasia (BPH) is a medical condition in which the prostate gland becomes enlarged. The enlargement of the prostate gland causes urinary tract problems by blocking the flow of urine out of the body. This happens because the prostate gland surrounds the urethra, which is the tube that carries the urine from the urinary bladder to out of the body, and so, the enlargement of the gland squeezes or blocks the urethra, causing discomfort and problems while urinating.

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In the U.S., the growing prevalence of this diseases, because of the surging geriatric population in the country, is rapidly becoming a major health issue. As a result, medical researchers are conducting extensive research and development (R&D) activities for developing advanced BPH treatment procedures. Moreover, the demand for BPH medications is also rising at an explosive pace in the country. Because of these factors, the U.S. benign prostatic hyperplasia (BPH) procedures market will advance rapidly in the coming years.

Amongst the various energy-based treatment procedures, the popularity of the laser-based procedures was found to be very high in the years gone by, because of the fact that these procedures are much more effective than the traditional treatment methods and are far less likely to cause various complications such as bleeding. There are many types of laser-based treatment procedures such as those involving thulium-, holmium lasers-, and green light lasers.

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Therefore, it can be said with complete certainty that the demand for benign prostatic hyperplasia treatment (BPH) procedures will rise enormously in the U.S. in the upcoming years, because of the growing prevalence of BPH in males and the rapid advancements and innovations being made in these procedures in the country.

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Surging Geriatric Population Supporting the Wet Age-Related Macular Degeneration Sector Growth

The growing prevalence of age-related macular degeneration (AMD), lack of specific treatment availability, and increase in geriatric population are driving the growth of the wet age-related macular degeneration market. The market is projected to generate revenue worth $10.4 billion in 2024, witnessing a CAGR of 7.1% during the forecast period (2019–2024).  AMD is a disease in which blurred vision or blindness occurs due to damage to the retina macula. Wet AMD is a type of AMD characterized by the growth of abnormal blood vessels under the retina and macula.

On the basis of product, the wet age-related macular degeneration market is categorized into Eylea, Avastin, Lucentis, and others. Out of these, during the historical period (2014–2018), the Eylea category witnessed the fastest growth, and it is expected to keep growing during the forecast period at a CAGR of 10.0%. This is mainly attributed to the surging demand for this medication due to its low cost as well as high efficiency in the management of exudative or wet AMD.

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The risk of developing AMD is directly proportional to age. With the number of people aged 60 years and above rising, the prevalence of AMD is also increasing. According to the World Population Prospects data published by the United Nations (UN), in 2017, there were about 962 million people in the age group 60 years or over across the globe, and the number is predicted to more than double by 2050, reaching 2.1 billion ultimately. Thus, it can be concluded that the geriatric population is rising faster than younger age groups.

Japan, Germany, Italy, and Portugal are among the nations with the largest population of elderly in the world. As older people are more prone to degenerative disorders, the increasing geriatric population in these countries is anticipated to contribute to the rising demand for drugs for wet AMD treatment, thus driving the wet age-related macular degeneration market during the forecast period.

Therefore, the surging geriatric population across the world is pushing the demand for drugs for treating wet AMD, resulting in the growth of the market.

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Opioid Induced Constipation Market Analysis, Demand, Growth Opportunities and Recent Trends by Leading Manufacturers and Regions

Opioids are directed to the patients suffering from the acute and chronic non-cancer pain. The opioids have numerous adverse intestinal effects, such as opioid-induced constipation. The opioids also affect the discharge of digestive enzymes that can sometime cause partial gastro paresis. Some of the most familiar symptoms of opioid-induced constipation includes, hard and dry stools, swelling, painful defecation, distention and protruded abdomen, tiredness, and loss of hunger. Some of the most common opioid-induced constipation therapy is the use of targeted therapies, OTC and off-label drugs and changing lifestyle.

  

On the basis of different form of drug the global opioid-induced constipation market can be bifurcated into two broad categories: solid and liquid. Some of the dominant market drivers for opioid-induced constipation includes, rising number of OIC patients, and widespread use of opioids treatment in chronic non-cancer pain. The current opioid-induced constipation market is led by the inexpensive and widely available laxatives. The clinical efficiency of laxatives is poor compared to its counterparts; however they still broadly used in constipation relief.

Lack of awareness about the opioid-induced constipation in patients, and the doctors are one of the dominant causes of off-label and OIC medications as majorly used treatment methods. However, the efficiency of these drugs is only the half of some of the other therapies. The entrance of superficially acting mu-opioid receptor rivals such as Movantikv or Moventig are driving the opioid-induced constipation market. Movantikv or Moventig drug targets only the fundamental reason of opioid-induced constipation without affecting the effect of the opioid drugs.

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Europe was the largest market of the opioid-induced constipation market in 2015 in terms of value. It is then followed by North America. The market dominance of Europe is attributed the presence of a large number of baby boomers population in the region. North America was the fastest growing market for opioid-induced constipation in 2014, the market size of North America is expected to surpass the Europe during the forecast period. The high growth of the market is attributed to the supportive government incentive in healthcare services in addition with the presence of a large pool of patients suffering from chronic pain.  

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In September 2014 the U.S. Food and Drug Administration (FDA) has approved methyl naltrexone bromide hypodermic injection, 12 mg/0.6ml, for the treatment of opioid-induced constipation for the patients using opioids non-cancer chronic pain. This approval from the FDA is expected to serve approx. 11 million patients in the U.S. who are suffering from opioid-induced constipation.

Based on the different form of therapy the global opioid-induced constipation market can be broadly categorized as non-tamper resistant formulations (non-TRFs) and tamper resistant formulations (TRF). The non-TRFs has the largest market share in 2014, however the TRFs is expected to more dominant treatment technology in upcoming years attributed mainly to the U.S. Food and Drug Administration (FDA) promotions and  broad pipeline of oral (TRFs) approval.

Some of the major players operating in the global opioid-induced constipation market include, AstraZeneca plc, Valeant Pharmaceuticals International Inc., Takeda Pharmaceutical Co. Ltd., Salix Pharmaceuticals, Ltd., Progenics Pharmaceuticals, Inc., Abbott Laborites, and Bayer AG among others.

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Influenza Vaccine Market by Therapeutics, Diagnostics, Patient, Drugs Policy and Regulatory Landscape

The global influenza vaccine market is growing significantly due increasing awareness about the pandemic influenza viruses and increasing government involvement for vaccination against influenza viruses.Massive unexplored influenza vaccine marketin the emerging economiesare creating ample opportunities for the global influenza vaccine marketto grow at a significant rate in the forecasted period.The advanced research and development facilities and new vaccine developments by the companies are propelling the demand for safe and efficacious influenza vaccine. Influenza (flu) is a respiratory disease caused by mainly two types of influenza viruses namely, influenza A and B viruses. Influenza A viruses are of two types based on the proteins on the surface of virus: hemagglutinin (H) and neuraminidase (N).

In global influenza vaccine industry, there is a trend of development of intranasal vaccine due to the ease of self administration. According to Centers for Disease Control and Prevention (CDC),in 2009, approximately 151,700 to 575,400 people died due to H1N1 influenza pandemic or swine flu across the globe. In addition, the organization also reported that most deaths due to 2009 flu pandemic occurred in Africa and Southeast Asia region. Several vaccines have been developed to prevent pandemic and seasonal influenza viruses using recombinant DNA technology and extensive researches are going on to develop efficient influenza vaccines using cell culture technology. Various governmental and non-governmental organizations have been actively involved in promoting and monitoring vaccination programs aimed at immunising people against seasonal influenza viruses. This in turn fuels the growth of global influenza vaccine market.

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 Some of the factors driving the growth of the global influenza vaccine market are increasing research and development activities,increasing investment by companies for the development of influenza vaccine, technological advancements in recombinant DNA technology, large number of population with no immunization against influenza viruses in emerging economies,increasing healthcare expenditure, and increasing involvement of government and non-government organizations.In addition, geriatric population and people suffering from chronic diseases are at higher risk of developing influenza virus infection; hence, aging population and increasing prevalence of chronic diseases are also driving the demand of influenza vaccine market. However, stringent regulatory framework and low accessibility to remote areas aresome of the factors restraining the growth of the global influenza vaccine market to some extent.

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Geographically, North America will be leading the global influenza vaccine market in the coming years, due to high awareness of influenza viruses, high healthcare expenditure, and increasing research and development activities.In addition, the U.S. Food and Drug Administration (FDA), recommends vaccination as the most effective method to prevent influenza; hence, fueling the growth of influenza vaccine market in NorthAmerica region. Asia-Pacificis the fastest growing region in the global influenza vaccinemarket. The major reasons for the fastest growth in the region are massive unexplored market (as large number of people donot have access to vaccination), increasing involvement of government, and increasing healthcare expenditure.

Some of the major players operating in the global influenza vaccine market are GlaxoSmithKline,Sanofi Pasteur, Inc., ID Biomedical Corporation, CSL Limited, Novartis, Protein Sciences Corporaton, MedImmune, LLC, Sinovac Biotech, Serum Institute of India, and Hualun Biologicalsamong others.

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Cytomegalovirus Retinitis Market Comprehensive Review of its Applications Growth Opportunities and Future Prospects

One of the major trends noticed in the cytomegalovirus retinitis market is usage of off-label drugs for the treatment of cytomegalovirus retinitis. Innovation of products focusing on better efficacy, growing demographics and growing economies in the developing countries, such as China and India, are some of the opportunities for global cytomegalovirus retinitis market.

Cytomegalovirus retinitis is eye disease caused due to retina inflammation of eye. The causative agent of the disease is cytomegalovirus, a herpes virus that affects the photosensitive cells of retina. After affecting the retina, the disease spreads from one eye to another eye, which can lead to blindness, if left untreated. Photophobia, blurred vision, seeing floaters and blind spots are the symptoms of cytomegalovirus retinitis. Cytomegalovirus retinitis usually affects people with weak immune system, including HIV affected patients. Various forms of cytomegalovirus retinitis medication are solutions, capsules, tablets and implants.

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Some of the major factors restraining the growth of the global cytomegalovirus retinitis market are lack of awareness among people for different types of eye diseases, rising healthcare cost in developing countries and lack of healthcare insurance. Majority of the population do not have proper access to primary healthcare services because of poverty and absence of health insurance, which is also hindering the growth of cytomegalovirus retinitis market. The other major challenge for the global cytomegalovirus retinitis market is lack of approved treatment guidelines by the World Health Organization (WHO).

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North America has the largest market for cytomegalovirus retinitis due to improved medical facilities and increasing occurrence of cytomegalovirus retinitis cases in the region. Asia-Pacific is growing with the highest rate among global cytomegalovirus retinitis market. In Asia-Pacific, China and India are the two fastest growing cytomegalovirus retinitis markets, attributed to raising government initiatives and support and large population in these countries.

Some of the major competitors of global cytomegalovirus retinitis market are, Shire Plc, F. Hoffmann-La Roche AG, Hospira Inc., Chimerix Inc., Gilead Sciences Inc., pSivida, Auritec Pharmaceuticals Inc., Sanofi S.A., and Isis Pharmaceuticals Inc.

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Restless Legs Syndrome Market Performance and Market Share, Sales Revenue and Major Manufacturers Performance, Gross Margin Analysis

Restless legs syndrome or RLS is a neurological disease. RLS is also called as Willis-Ekbom disease. Patients suffering from RLS disease have an irresistible desire to move their feet. The continual movement of the legs leads to pain in the limbs, which leads to the unusual sleep pattern of patients.

The exact reason behind the restless legs syndrome is not known precisely, however, it is believed the disease is caused due to genetic factors or due to iron deficiency in the brain or due to the disorders in dopaminergic balance.

The exact treatment of this disease is not present till now. However the available drug in the market helps in the indicative treatment of the disease. Some of the drug in the restless legs syndrome market such as sulfonamide by safinamide by Newron Pharmaceuticals reduces the symptoms by novel action such as potent, reversible and selective inhibition of MAO-B, without disturbing the MAO-A and dopamine uptake. This enhances the glutamate release and dopaminergic function of the patients; it also reduces the dopamine degradation. One other drug: SER-214 manufacture by Serina is used widely in the restless legs syndrome treatment; it uses a water-soluble polymer poly (2-alkyloxazoline)-based drug delivery technology this drug can be combined with the polymer and transported to the patients.

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Based on the different product type the global restless legs syndrome market can be broadly classified as Mirapex/Sifrol/Mirapexin, Neupro/Leganto, Requip, and HORIZANT/Regnite. On the basis various disease type the global restless legs syndrome market can be broadly bifurcated as etiology and pathogenesis, iron deficiency, genetic factors, neurological disturbances and others. Based on the mode of the therapy the global restless legs syndrome market can be broadly segmented into two broad categories: pharmacological therapy and non-pharmacological therapy.

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Some of the major players operating in the global restless legs syndrome market include, GlaxoSmithKline plc., Ligand Pharmaceuticals Incorporated, axxonis Pharma AG, Kyowa Hakko Kirin Co., Jazz Pharmaceuticals, Inc., Omeros Corporation, Manhattan Pharmaceuticals, Boehringer Ingelheim GmbH, UCB SA.

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Nuclear Medicine (Radiopharmaceuticals) Market by Overview, Growth Opportunities, Manufacturing Cost Structure Analysis, Outlook and Industry Insights Forecast to 2024

The global nuclear medicine/radiopharmaceuticalsmarket is growing significantly due to increasing prevalence of cancer and cardiovascular diseases, and advances in nuclear medicine imaging procedures. High demand of nuclear medicines in emerging economies and potential radiopharmaceuticals in the pipeline create ample opportunities for the nuclear medicine/radiopharmaceuticals market to grow at a considerable rate in the coming years.

The advances in neurological applications and development of new products by the companies are supporting to address the demand for cost effectiveness of radiopharmaceuticals. Nuclear medicine imaging procedures are non-invasive and can be used for the treatment of several diseases, such as cancers, cardiovascular diseases, and neurological disorders.

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The nuclear medicine/radiopharmaceuticals market is segmented on the basis of type, application, and region. On the basis of type, the nuclear medicine/radiopharmaceuticals market can be segmented as diagnostics and therapeutics. The diagnostics segment leads the nuclear medicine/radiopharmaceuticals market. The diagnostics segment can be further categorized into single-photon emission computed tomography (SPECT) and positron emission tomography (PET). SPECT segment will be leading the nuclear medicine/radiopharmaceutical diagnostics market in the coming years due to its wider availability and less cost. The therapeutics segment can be further categorized into beta emitters, alpha emitters, and brachytherapy isotopes. The beta emitters will be the leading segment in the global nuclear medicine/radiopharmaceutical therapeutics market.

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Geographically, North America will be leading the global nuclear medicine/radiopharmaceuticals market in the coming years due to increasing prevalence of cancer, ready availability of radiopharmaceuticals, popularity of nuclear medicine among physicians, and technological advancements.

Asia-Pacific is the fastest growing region in the global nuclear medicine/radiopharmaceuticals market. The major reasons for the fastest growth in the region are increasing healthcare expenditure, and rising awareness of radiopharmaceuticals among healthcare providers. Moreover, Japan will be leading the nuclear medicine/radiopharmaceuticals market in Asia-Pacific region in the coming years.

Some of the major players operating in the global nuclear medicine/radiopharmaceuticals market are GE Healthcare, Bayer Healthcare, Cardinal Health Inc., Eczacibasi-Monrol Nuclear Products, Bracco Imaging S.p.A, Nordion Inc., Lantheus Medical Imaging Inc., Advanced Accelerator Applications S.A, Mallinckrodt plc, and IBA Molecular Imaging.

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Human Growth Hormone Market Share, Strategies, Emerging Technologies, Growth Rate Analysis, Trends and Forecast

The global human growth hormone market is witnessing growth due to the presence of large pool of patients and technological advancements. The increasing compliance for human growth hormone drugs and massive unexplored market in the emerging economies, such as India and China are creating opportunities for the growth of the global human growth hormone market. The advanced research and development facilities, and new drug developments by the key players are propelling the demand for improved and cost effective human growth hormones; further fuelling the growth of the global growth hormone market.

Some of the factors driving the growth of the global human growth hormone market are increasing demand for human growth hormone drugs, increasing incidences of human growth hormone deficiency diseases, growing geriatric population, and technological advancements, such as recombinant DNA technology for the development of human growth hormone drugs. In addition, several major players are investing heavily and collaborating among each other for the research and development of human growth hormone drugs, which is fueling the growth of the global human growth hormone market. However, stringent regulatory approvals, high cost of treatment, and adverse effects associated with the usage of synthetic human growth hormones are some of the factors restraining the growth of the global human growth hormone market to some extent.

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Geographically, North America leads the global human growth hormone market, due to increasing proportion of aged population, high incidences of turner syndrome, short bowel syndrome, human growth hormone deficiency and Noonan syndrome. Moreover, the high demand of human growth hormone drugs as performance enhancer and anti-aging drug in North America is driving the growth of the human growth hormone market in the region. Asia-Pacific is the fastest growing region in the global human growth hormone market, which is driven by increasing healthcare expenditures and high incidences of growth hormone deficiency disorders. Moreover, the human growth hormone market is growing due to increasing disposable income and large geriatric population in the emerging countries, such as India and China.

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Some of the major players operating in the global human growth hormone market are Pfizer Inc., F. Hoffmann-La Roche AG, Novo Nordisk A/S, Merck KGaA, Eli Lilly and Company, Novartis AG, and Teva Pharmaceutical Industries Ltd.

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Global Endometrial Cancer Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2024

Global endometrial cancer therapeutics market is expected to witness significant growth as there are less number of approved drugs for treatment of endometrial cancer, leading to an increased opportunity for the drug manufacturers. High prevalence of cancer and rising demand for safe and effective medications can be attributed as the major drivers of this market. The regulatory bodies such as USFDA and EMA are supporting the growth of the global market by providing increased funding, designations and grants for speeding up the drug development process.

Endometrial cancer is the malignancy that develops in the layers of the cells that forms endometrium, lining of uterus. The precise cause of endometrial cancer is still unknown but it is assumed that estrogen may be involved in developing endometrial cancer, as estrogen helps in the formation of the endometrial lining. Obesity, polycystic ovary syndrome, infrequent periods and history of endometrial polyps can increase the risk of endometrial cancer. Women with diabetes, high blood pressure or breast cancer are at a greater risk of having endometrial cancer. Abnormal vaginal bleeding, bleeding between periods or after menopause, lower abdominal cramps or clear vaginal discharge after menopause are some of the main symptoms of endometrial cancer.

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High prevalence and recurrence of endometrial cancer after treatment with chemotherapy are the major driving factors driving the endometrial cancer therapeutic market.  Growing prevalence of obesity in women aged 50 years or above is also contributing in the growth of the endometrial cancer therapeutics market globally. Apart from this, safety concerns after chemotherapy, hormone therapy and radiation therapy restrict the medications for the treatment of endometrial cancer.

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Geographically, North America is expected to be the largest market for endometrial cancer therapeutics treatment, owing to the large number of research and development activities ad high healthcare expenditure. Europe is expected to hold the second largest share in the global market owing to growing product availability in the region.

Some of the key players operating in the global endometrial cancer therapeutics market are AstraZeneca Plc., Novartis AG, Bristol-Myers Squibb Company, Pfizer, Inc. and R-Pharm-US LLC.

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Medical Marijuana Market Opportunities by Types, Demand, Top Manufactures and Application in Grooming Regions

The global medical marijuana market is expected to witness considerable growth during the forecast period on account of the rise in the number of countries legalizing the consumption of the drug for medicinal purposes and its potential application in the treatment of several chronic diseases. Increasing awareness among healthcare providers and individuals regarding the benefits of medicinal marijuana will also support the market growth in the future. Moreover, growing investments (by both private and public organizations) in research associated with the use of marijuana for medical purposes are expected to continue driving the market growth.

On the basis of application, the medical marijuana market is categorized into chronic pain, arthritis, migraine, cancer, and others. Among these, chronic pain is the largest application area of medical marijuana and is expected to continue leading the market during the coming years. This can be attributed to the increasing prevalence of chronic diseases and rising awareness among patients and healthcare providers regarding the potential benefits of using marijuana for relieving chronic pain.

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Globally, North America was the largest revenue generator in the medical marijuana market in 2017, because of high investments in research and development activities to investigate the potential medical applications of cannabinoids. Moreover, Canada and some states of the U.S. are planning to legalize the usage of marijuana for medical as well as recreational purposes. For instance, by October 2018, Canada plans to legalize the drug use by adults. As per the current medical regime associated with cannabis, patients are allowed to access cannabis under the authorization of their healthcare providers. 

Thus, government initiatives to spread awareness about the medical application of marijuana and legalize its usage are expected to contribute to the market growth in the near future.

Some of the major factors contributing to the growth of the medical marijuana industry are the increasing prevalence of chronic diseases, growing investments by public and private organizations to conduct research focusing on the medical applications of marijuana, and rising awareness among healthcare providers toward the usage of the drug.

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Several research projects have been funded by the National Institute of Health (NIH) and the National Institute on Drug Abuse (NIDA) to explore the possible benefits of marijuana in different medical conditions. Furthermore, increasing consumption of cannabinoid-based drugs approved for certain disorders is promoting the market growth. For instance, nabiximols (Sativex), a mouth spray containing two cannabinoids of marijuana, that is, tetrahydrocannabinol (THC) and cannabidiol (CBD), is used for treating muscle control problems caused by multiple sclerosis. Nabiximols is approved in the U.K., Canada, and several European countries, and studies are being conducted for the drug approval in the U.S. as well.

Players, through the acquisition of other similar companies, are strengthening their position in the medical marijuana market. For instance, in October 2018, Wuhan General Group [China] Inc. (Wuhan) announced that it signed a letter of intent to acquire MJ MedTech Inc. (MedTech), a manufacturer of medical marijuana and cannabidiol (CBD) products. Through this acquisition, Wuhan expects to gain from MedTech’s insights, market value, and advanced technology to establish its presence in the U.S., Canadian, and European markets and strengthen its position in the medical CBD product business.

Some of the other key players in the medical marijuana industry are Canopy Growth Corporation, Aurora Cannabis Inc., Medical Marijuana Inc., GW Pharmaceuticals PLC, Aphria Inc., CanniMed Ltd., Tilray Inc., and Emerald Health Therapeutics Inc.

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Diabetic Retinopathy Market Comprehensive Review of its Applications Growth Opportunities and Future Prospects

Diabetic retinopathy refers to an eye disorder that damages or harms the blood vessels of the retina. Diabetic retinopathy can cause permanent blindness. Chronic diabetes is a major root of diabetic retinopathy.

The treatment procedure of diabetic retinopathy depends on the various stages of diabetic retinopathy. It is one of the most dominant reasons of blindness in U.S adults. According to WHO, about 347 million patients were suffering from diabetes globally as of 2012, and among those 347 million patients 11% of those were effected from diabetic retinopathy.  In the U.S. alone, there were 4.1 million people were impacted from the diabetic retinopathy as of 2012. 

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North America was the largest market for diabetic retinopathy in 2014. The market dominance of North America is attributed to the high obesity rate and large diabetic patients in this region. Moreover the supportive government initiative is also one of the important drivers of the market in this region.

Europe was the second largest market of diabetic retinopathy in 2014, the large population of baby boomers in Europe is one of the dominate growth factors for the diabetic retinopathy market in this region. Asia Pacific is expected to show the highest growth over the next five years. The lucrative growth of the diabetic retinopathy market in Asia Pacific is attributed to the presence of a large number of diabetic patients in India and China. Moreover, growing health awareness coupled with rising expenditure on healthcare services is also fueling the diabetic retinopathy market in this region. Country wise the U.S. is the largest market of diabetic retinopathy in North America. Germany, Spain, Italy, U.K and France are some of the major diabetic retinopathy market in Europe. China, Japan, India are some of the major market diabetic retinopathy in Asia Pacific region. Under Rest of the World section Brazil is the largest market of diabetic retinopathy.   

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Some of the major players operating in the global diabetic retinopathy market include, Bayer AG, Pfizer Inc., F. Hoffmann-La Roche Ltd., Regeneron Pharmaceuticals Inc., Novartis AG, Valeant Pharmaceuticals International Inc., Abbott Laboratories Ltd., Alimera Sciences Inc., Ampio Pharmaceuticals Inc., Bausch & Lomb Inc., Boehringer Ingelheim GmbH, iCo Therapeutics Inc., Lupin Ltd., Parexel International Corp., Quark Pharmaceuticals Inc., Thrombogenics NV, and Vitreoretinal Technologies Inc. 

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Diabetic Nephropathy Market Opportunities by Types, Demand, Top Manufactures and Application in Grooming Regions

The increase in research and development funds for drug discovery followed by growing awareness of kidney-related disorders, and diabetes are the major factors driving the expansion of the global diabetic nephropathy market.

Diabetes is a disease defined by high blood sugar level, caused by inappropriate functioning of the pancreas (the organ which secretes insulin in the body). Nephropathy means kidney impairment or damage. Diabetic nephropathy is the impairment or damage to the kidneys caused by diabetes.

It is a disease which affects the kidney glomerulus and one of the most major issues for diabetic patients. Not only the person with diabetes has to undergo kidney impairment, but also the acute cases of diabetic nephropathy could lead to kidney miscarriage. The disease affects the kidneys in a way that makes it futile. Progressive growth in proteinuria and failure in renal function, hypertension, and high risk of cardiovascular disease are the major side effects of chronic diabetic nephropathy. Blood pressure (BP) control is necessary in minimizing the progression of diabetic nephropathy. Irrespective of the agent used, lower blood pressure in type II diabetics could slow down the start and progression of diabetic nephropathy.

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On the basis of mode of treatment, the global diabetic nephropathy market is segmented into disease modifying therapies and others. Disease modifying therapies is further categorized into diuretics, angiotensin-converting enzyme inhibitors, antioxidant inflammation modulator, angiotensin receptor blockers, renin inhibitors, calcium channel blockers, connective tissue growth factor inhibitors, monocyte chemoattractant proteins inhibitor, G protein-coupled receptors and endothelin (a receptor antagonist).

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Various government programs are spreading cognizance about diabetes and related renal complications in North America. For example, the National Kidney Disease Education Program (NKDEP) is one of the most important programs organized by the U.S. government, for growing awareness about the various kidney diseases.

Lack of complete therapeutic management for diabetic nephropathy, longer approval time for drugs as well as, harsh regulatory requirements are hampering the market growth of global diabetes nephropathy market.

Some of the major competitors in the global diabetic nephropathy market are Novartis AG, Merck & Co., Inc., Pfizer Inc., Abbott Laboratories, Sanofi, Eli Lilly and Company, Reata Pharmaceuticals, Inc., Bayer AG, AbbVie Inc., and Mitsubishi Tanabe Pharma Corporation.

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Asthma Market to Witness the Highest Growth Globally in Coming Years

Asthma is a respiratory condition, where the airways become inflamed and narrow, which can cause a serious and incurable condition if left untreated. Breathlessness, wheezing and coughing are some of the symptoms of asthma and it can be controlled by avoiding triggers and with the help of drug therapy. Environmental triggers may vary from consumer to consumer but it can include exercise, smoke, cold air and other allergens such as pollen, dust mites, and infections. The wheezing in asthma begins when the chemicals present in the lungs overreact to the dust mites, cold air and exercise.

According to Centers for Disease Control and Prevention (CDC), asthma is an ordinary chronic airway disorder which is characterized by swelling of air passages that convey air from mouth and nose to lungs. Asthma is caused generally due to allergies leading to inflammation of lungs. GlaxoSmithKline Pharmaceuticals Limited and Novartis AG are developing once-a-day combination products that are longer acting than currently available drugs and more suitable for patients due to its advantage of being taken only once a day.

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Based on drug class, the global asthma market can be categorized bronchodilators, combination therapies, mast cell stabilizers, leukotriene antagonists and immunosuppressants. On the basis of route of administration, the global market is segmented into oral, inhaled and other route of administrations.

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Daily exposure to hazardous working environment, influx of pollutants in the air, increase in population susceptible to indoor air pollutants, increase in disposable income, increasing population of smokers, improved healthcare facility, and growing aging population are some of other the major factors that are driving the growth of asthma market. Factors that are restraining the growth of asthma market are high cost of asthma treatment, patent expiry of many best-seller brands and long treatment continuation. Additionally, lack of diagnostic tools for reliable asthma diagnosis in young children is also limiting the growth of global asthma market.

Some of the major competitors of global asthma market are, Ono Pharmaceutical Co., Ltd., GlaxoSmithKline plc, Teva Pharmaceutical Industries Ltd. Merck & Co., Inc., Astrazeneca plc, Sunovion Pharmaceuticals, Inc., Novartis AG, Boehringer Ingelheim GmbH, Koninklijke Philips N.V., and F. Hoffmann La-Roche Ltd.

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Benign Prostatic Hyperplasia Therapeutics Market Epidemiology Analysis, Therapy, Growth and Demand Forecast to 2023

The global benign prostatic hyperplasia therapeutics market is expected to witness significant growth, as increased number of effective treatments are available for cancer. Increasing awareness regarding various cancer treatment drugs, technological advancements, and growing demand for safe and effective medications are acting as the major growth drivers for the benign prostatic hyperplasia therapeutics market. Globally, regulatory bodies are adding to the growth of the market with provision of funding, grants and designations. Thus, these regulatory bodies are amplifying the drug development process. 

Benign prostatic hyperplasia is also known as benign prostatic obstruction or benign prostatic hypertrophy, is a disease state in men, caused by prostate gland enlargement. Prostate develops in dual phase in entire life – the first phase occurs in initial phase of puberty, followed by the second phase that usually begins at the age of twenty-four and remains for most of a person’s life. Benign prostatic hyperplasia is a common problem in men aged above 50 years, and it occurs in the second phase of growth of prostate. However, the disease can also arise in men aged below 40 years, with the probabilities of its occurrence increasing with age.

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Aging population is the major factor on which the benign prostatic hyperplasia therapeutics market is mostly dependent. Asia-Pacific and European markets for benign prostatic hyperplasia therapeutics are likely to observe significant growth rates, during the forecast period, due to increase in aging population in these regions. The Latin American and North American markets for benign prostatic hyperplasia therapeutics are also projected to observe strong growth rates, during the forecast period.

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Some of the key players operating in the global benign prostatic hyperplasia therapeutics market include Sandoz, Inc., Sanofi Aventis, Labopharm, Inc., Pfizer, Inc., and Teva Pharmaceuticals, Inc.

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