The study analyzed that the psoriasis therapeuticspipeline comprises approximately 150 drug candidates in different stages of
development. Psoriasis is a chronic inflammatory disorder that causes red
patches covered with white scales on the skin. It is characterized when a
person’s immune system sends defective signals which results in skin cells to
grow rapidly. The body does not shed these excess skin cells and pile up on the
surface of the skin, causing patches of psoriasis to appear. There are five
types of psoriasis namely, plaque psoriasis or psoriasis vulgaris, guttate
psoriasis, inverse psoriasis or flexural psoriasis or intertriginous psoriasis,
pustular psoriasis, and erythrodermic or exfoliative psoriasis.
According to the research findings, majority of the
drug candidates in the pipeline are being developed to be administered by
topical route.
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MC2 Therapeutics A/S is using PAD technology platform
for the development of MC2-01 for the treatment of psoriasis. PAD technology
platform offers a number of unique advantages in the development of new topical
drugs. PAD vehicles are special made oil-in-water dispersions in which the
internal oil phase is stabilized by encapsulation in a thin yet robust aqueous
film of surfactants.
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Some of the key players developing drugs for the
treatment of psoriasis include Amgen Inc., Maruho Co., Ltd., Boehringer
Ingelheim GmbH and others.
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