Adenosine
5-monophosphate activated protein kinase (AMPK) plays an important role
in regulation of homeostasis. Dysregulation of AMPK can result in many diseases
which includes obesity and type 2 diabetes. Several studies have also suggested
that AMPK are also associated with the development of neurological diseases and
cancer.
Esperion Therapeutics Inc. is in the process of developing
Bempedoic acid as a small molecule which acts as an AMPK stimulant for the
treatment of hypercholesterolemia, dyslipidaemia, and hypertension. Betagenon
AB, Boehringer Ingelheim International GmbH, and Poxel SA are some other
companies having pipeline AMPK modulators for the management of several
diseases.
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The report provides a comprehensive understanding of the
pipeline activities covering all drug candidates under various stages of
development, with detailed analysis of pipeline and clinical trials.
Pipeline analysis of drugs by phases includes product
description and development activities including information about clinical
results, designations, collaborations, licensing, grants, technology and
others.
