Adrenocortical Carcinoma Therapeutics - Pipeline Analysis, Collaborations, and Other Developments

Adrenocortical carcinoma, also known as adrenal cortex carcinoma, is a rare form of cancer that occurs at the cortex layer of the adrenal gland. There are two adrenal glands present in the human body: one at the top of each kidney. Each adrenal gland is comprised of two...

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Cathepsin K Inhibitors Therapeutics - Pipeline Analysis 2019 Clinical Trials & Results

Cathepsin K is a protease enzyme which is coded by CTSK gene. The function associated with the gene involves bone remodelling and resorption. Cathepsin K is a member of peptidase C1 protein family and expressed mainly in osteoclasts. The protein has high specificity...

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Adenosine 5-Monophosphate Activated Protein Kinase (AMPK) Modulators Therapeutics - Pipeline Analysis 2018

Adenosine 5-monophosphate activated protein kinase (AMPK) plays an important role in regulation of homeostasis. Dysregulation of AMPK can result in many diseases which includes obesity and type 2 diabetes. Several studies have also suggested that AMPK are also associated...

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Aurora Kinase Inhibitor Therapeutics - Pipeline Analysis 2019

Aurora kinase are proteins that function as mitotic regulators and are aberrantly expressed in cancerous cells. Aurora kinase inhibitors target these aberrantly expressed regulators, provides genetic stability and prevents tumorigenesis. Several studies have demonstrated...

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Hepatocyte Growth Factor (HGF) Inhibitor Therapeutics - Pipeline Analysis 2019

Hepatocyte growth factor (HGF) is secreted by human pancreatic stellate cells and present predominantly on cancer cells. Thus, HGF inhibitors has emerged as an effective therapy in preventing local tumor growth. Also, studies have demonstrated that HGF inhibitors are significantly...

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Interleukin 8 Inhibitors Therapeutics - Pipeline Analysis 2019

Interleukin 8 is a chemokine produced by various immune cells. They promote angiogenesis, proliferation and development of cancerous cells. The other diseases which are associated with interleukin 8 are depression, schizophrenia, bipolar disorder, migraine, Alzheimer’s...

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Mitogen-Activated Protein Kinase (MAPK) Inhibitors Therapeutics - Pipeline Analysis 2019

Mitogen-activated protein kinase (MAPK) are ubiquitous regulators of many cellular functions including cell proliferation, cellular growth, inflammatory responses to stress signals and cell differentiation. MAPK pathway, involves three main kinases, Raf, MEK and ERK, has...

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MDM2 Protein Inhibitors Therapeutics - Pipeline Analysis 2019

MDM2 protein are powerful oncogene which is overexpressed in various cancers, including breast cancer and sarcoma. There are many small molecule drug candidates that are being developed as MDM2 protein inhibitors as monotherapy or combination therapy for the treatment of...

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Interleukin Receptor Modulators Therapeutics - Pipeline Analysis 2019, Clinical Trials & Results, Patents

Interleukin receptors are a group of cytokine receptors that are expressed by leukocytes. Interleukin receptors play an important role in the functioning of the immune system. However, with complete knowledge of their role in pathogenesis of different diseases from allergic...

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Endothelin Antagonists Therapeutics - Pipeline Analysis , Patents, Designations, Collaborations, and Other Developments

Endothelin antagonists are drug candidates that acts against endothelin receptors and generate pharmacological actions such as blocking the vasoconstriction and mediate vasodilatation. Endothelin-1 is a peptide which is comprised of 21 amino acids and formed by vascular endothelium....

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Epidermal Growth Factor Receptor (EGFR) Antagonists Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations

Epidermal growth factor receptors (EGFR) are a group of receptor tyrosine kinase (RTK) that plays a major role in cell proliferation, survival and differentiation. In most of the cancer, EGFR are amplified and overexpressed, due to dysregulation, resulting in cancer development. EGFR...

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Galectin Inhibitor Therapeutics - Pipeline Analysis , Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments

Galectins belong to the family of animal lectins and perform function by interacting with cytoplasmic and nuclear proteins, cell-surface and extracellular matrix glycoproteins and glycolipids to modulate signalling pathways. Studies have shown the crucial roles of galectin...

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Benign Prostatic Hyperplasia (BPH) Procedures And its Growth prospect in the Near Future

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Prevalence of Skin Diseases Accelerating the Dermatology Drugs Sector Growth

The human skin functionality decreases with age, which leads to problems such as reduced subcutaneous fat, slow healing, raised sensitivity to ultraviolet (UV) radiation, and increased susceptibility to skin infections.  Hence, the growing geriatric population results in...

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Surging Geriatric Population Supporting the Wet Age-Related Macular Degeneration Sector Growth

The growing prevalence of age-related macular degeneration (AMD), lack of specific treatment availability, and increase in geriatric population are driving the growth of the wet age-related macular degeneration market. The market is projected to generate revenue worth $10.4...

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Uveitis Treatment Market Share Analysis of The Top Industry Players, Growth Opportunities and Country Level Segments

Globally, North America is the largest, while Asia-Pacific is the fastest growing uveitis treatment market. The uveitis treatment market is witnessing significant growth, due to increasing prevalence of uveitis and related complications. The global uveitis treatment market...

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Protein A Resin Market to Witness the Highest Growth Globally in Coming Years

The global protein A resin market is expected to witness considerable growth during the forecast period due to the increasing research and development activities and increasing prevalence of chronic diseases. High traction for monoclonal antibodies in biopharmaceutical industry...

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Pompe Disease Market - Epidemiology Analysis, Therapy, Growth and Demand Forecast to 2024

The pompe disease market is growing at a significant rate mainly due to special provisions for orphan drugs. Regulatory assistance in emerging nations is one of the major trends seen in the pompe disease market. Pompe disease is a type of lysergic acid diethylamide (LSD)....

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Pancreatic Cancer Therapeutics Market - Epidemiology Analysis, Therapy, Development, Growth and Demand Forecast to 2024

The global pancreatic cancer therapeutics market holds numerous opportunities for the key players, as pancreatic cancer is a highly challenging disease among all types of cancer, which has no specific treatment available for it, as of now. Also, growing incidence of cancer...

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Integrated CDSS Segment Expected to Realize Fastest Growth in the Global CDSS Market, During Forecast Period

The clinical decision support system market size is expected to cross $1.5 billion by 2022, growing at a CAGR of 21.5% between 2016-2022. The CDSS market is driven by five major factors, including growing demand for advanced healthcare information systems, growing investments...

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Pain Management Drugs Market Segmental Analysis by Therapeutics, Diagnostics, Patient, Drugs Policy and Regulatory Landscape

The growing geriatric population and increasing demand of innovative and advanced pain relaxing medications around the world are the predominant growth drivers for the global pain management drugs market. Additionally, the increasing number of hospitalization cases; unmet...

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